DPP-4
Also: dipeptidyl peptidase-4, dipeptidyl peptidase IV, DPP4
A serine protease present in plasma and on cell surfaces that cleaves dipeptides from the N-terminus of peptides with proline or alanine at position 2. Responsible for the rapid degradation of native GLP-1 and GHRH. Inhibited by the gliptin class of diabetes drugs.